The evolution of virulence of West Nile virus in a mosquito vector: implications for arbovirus adaptation and evolution

@inproceedings{Ciota2012TheEO,
  title={The evolution of virulence of West Nile virus in a mosquito vector: implications for arbovirus adaptation and evolution},
  author={Alexander T. Ciota and Dylan J. Ehrbar and Amy C. Matacchiero and Greta Van Slyke and Laura D Kramer},
  booktitle={BMC Evolutionary Biology},
  year={2012}
}
Virulence is often coupled with replicative fitness of viruses in vertebrate systems, yet the relationship between virulence and fitness of arthropod-borne viruses (arboviruses) in invertebrates has not been evaluated. Although the interactions between vector-borne pathogens and their invertebrate hosts have been characterized as being largely benign, some costs of arbovirus exposure have been identified for mosquitoes. The extent to which these costs may be strain-specific and the subsequent… CONTINUE READING
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