The evolution of the therapeutic strategy in hepatitis C: features of sofosbuvir and indications.

@article{Alberti2014TheEO,
  title={The evolution of the therapeutic strategy in hepatitis C: features of sofosbuvir and indications.},
  author={Alfredo Alberti and Sara Piovesan},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  year={2014},
  volume={46 Suppl 5},
  pages={S174-8}
}
The treatment of chronic hepatitis C virus infection is rapidly evolving with the entry into the therapeutic armamentarium of a series of new and highly effective direct antiviral agents, targeted to the different virus structures involved in hepatitis C virus replication and assembly. Sofosbuvir is considered, without controversies, the most promising single direct antiviral agent in the current scenario. The pharmacological properties of sofosbuvir allow a single oral daily administration and… CONTINUE READING
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