The evolution of the therapeutic approach to membranous nephropathy.

@article{Ponticelli2020TheEO,
  title={The evolution of the therapeutic approach to membranous nephropathy.},
  author={Claudio Ponticelli and Passerini Patrizia and Lucia Del Vecchio and Francesco Locatelli},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2020}
}
  • C. Ponticelli, P. Patrizia, +1 author F. Locatelli
  • Published 24 March 2020
  • Medicine
  • Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Primary membranous nephropathy (MN) is a frequent cause of nephrotic syndrome (NS) in adults. In untreated patients, the outcome is variable, with one-third of the patients entering remission while the remaining ones show persisting proteinuria or progression to end-stage renal disease. Randomized clinical trials reported the efficacy of a 6-month regimen alternating intravenous and oral glucocorticoids with an alkylating agent every other month. The potential side effects of this regimen were… Expand
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