The evolution of the mitochondrial D-loop region and the origin of modern man.

@article{Pesole1992TheEO,
  title={The evolution of the mitochondrial D-loop region and the origin of modern man.},
  author={Graziano Pesole and Elisabetta Sbis{\`a} and Giuliano Preparata and Cecilia Saccone},
  journal={Molecular biology and evolution},
  year={1992},
  volume={9 4},
  pages={
          587-98
        }
}
The origin of modern man is a highly debated issue that has recently been tackled by using mitochondrial DNA sequences. The limited genetic variability of human mtDNA has been explained in terms of a recent common genetic ancestry, thus implying that all modern-population mtDNAs originated from a single woman who lived in Africa less than 0.2 Mya. This divergence time is based on both the estimation of the rate of mtDNA change and its calibration date. Because different estimates of the rate of… CONTINUE READING

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