The evolution of the concept of the use of surgical castration in the palliation of breast cancer in pre-menopausal females.

@article{Macmahon1976TheEO,
  title={The evolution of the concept of the use of surgical castration in the palliation of breast cancer in pre-menopausal females.},
  author={C E Macmahon and Jennifer L Cahill},
  journal={Annals of surgery},
  year={1976},
  volume={184 6},
  pages={
          713-6
        }
}
The understanding of the association of mammalian ovarian function with lactation was common knowledge to dairy-men early in the 19th century or earlier. This thesis reviews the application of these empiric observations to lactation in humans by Beatson of Glasgow, supported by his preliminary laboratory investigations. Beatson noted the cellular anatomic similarity between pre-gestational breast and carcinoma. This study reviews the progressive development of the successful clinical… CONTINUE READING

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