The evolution of reversible switches in the presence of irreversible mimics.

@article{Lancaster2009TheEO,
  title={The evolution of reversible switches in the presence of irreversible mimics.},
  author={Alexander K Lancaster and Joanna Masel},
  journal={Evolution; international journal of organic evolution},
  year={2009},
  volume={63 9},
  pages={2350-62}
}
Reversible phenotypic switching can be caused by a number of different mechanisms including epigenetic inheritance systems and DNA-based contingency loci. Previous work has shown that reversible switching systems may be favored by natural selection. Many switches can be characterized as "on/off" where the "off" state constitutes a temporary and reversible loss of function. Loss-of-function phenotypes corresponding to the "off" state can be produced in many different ways, all yielding identical… CONTINUE READING

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