The evolution of meiosis: recruitment and modification of somatic DNA-repair proteins.

@article{Marcon2005TheEO,
  title={The evolution of meiosis: recruitment and modification of somatic DNA-repair proteins.},
  author={Edyta Marcon and Peter B. Moens},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2005},
  volume={27 8},
  pages={795-808}
}
Several DNA-damage detection and repair mechanisms have evolved to repair double-strand breaks induced by mutagens. Later in evolutionary history, DNA single- and double-strand cuts made possible immune diversity by V(D)J recombination and recombination at meiosis. Such cuts are induced endogenously and are highly regulated and controlled. In meiosis, DNA cuts are essential for the initiation of homologous recombination, and for the formation of joint molecule and crossovers. Many proteins that… CONTINUE READING
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