The evolution of chronic infection strategies in the α-proteobacteria

  title={The evolution of chronic infection strategies in the α-proteobacteria},
  author={Jacques Batut and Siv G. E. Andersson and David O'Callaghan},
  journal={Nature Reviews Microbiology},
Many of the α-proteobacteria establish long-term, often chronic, interactions with higher eukaryotes. These interactions range from pericellular colonization through facultative intracellular multiplication to obligate intracellular lifestyles. A common feature in this wide range of interactions is modulation of host-cell proliferation, which sometimes leads to the formation of tumour-like structures in which the bacteria can grow. Comparative genome analyses reveal genome reduction by gene… CONTINUE READING
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