The evolution of a mechanism of cell suicide.

  title={The evolution of a mechanism of cell suicide.},
  author={Neil W. Blackstone and Douglas R Green},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  volume={21 1},
In the vertebrates, programmed cell death or apoptosis frequently involves the relocalization of mitochondrial cytochrome c to the cytoplasm. This prominent role in the regulation of apoptosis is in addition to the primary function of cytochrome c in the mitochondrial electron transport chain. These seemingly divergent roles become plausible when considering the symbiotic origin of the mitochondrion. Symbiosis involves conflicts between levels of selection, in this case between the primitive… CONTINUE READING

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