The evidence for functional non-CpG methylation in mammalian cells.

@article{Patil2014TheEF,
  title={The evidence for functional non-CpG methylation in mammalian cells.},
  author={Vibha Patil and Robyn Lynne Ward and Luke B. Hesson},
  journal={Epigenetics},
  year={2014},
  volume={9 6},
  pages={823-8}
}
In mammalian genomes, the methylation of cytosine residues within CpG dinucleotides is crucial to normal development and cell differentiation. However, methylation of cytosines in the contexts of CpA, CpT, and CpC (non-CpG methylation) has been reported for decades, yet remains poorly understood. In recent years, whole genome bisulphite sequencing (WGBS) has confirmed significant levels of non-CpG methylation in specific tissues and cell types. Non-CpG methylation has several properties that… CONTINUE READING
Highly Cited
This paper has 90 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

90 Citations

020406020142015201620172018
Citations per Year
Semantic Scholar estimates that this publication has 90 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…