The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis.

@article{Hickner1992TheET,
  title={The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis.},
  author={Robert C. Hickner and Hans G Rosdahl and Ivar Borg and Urban Ungerstedt and Lennart Jorfeldt and Jan Henriksson},
  journal={Acta physiologica Scandinavica},
  year={1992},
  volume={146 1},
  pages={87-97}
}
We have investigated the feasibility of monitoring local skeletal muscle blood flow in the rat by including ethanol in the perfusion medium passing through a microdialysis probe placed in muscle tissue. Ethanol at 5, 55, or 1100 mM did not directly influence local muscle metabolism, as measured by dialysate glucose, lactate, and glycerol concentrations. The clearance of ethanol from the perfusion medium can be described by the outflow/inflow ratio ([ethanol]collected dialysate/[ethanol]infused… CONTINUE READING
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