The equilibrium partition function and base pair binding probabilities for RNA secondary structure

  title={The equilibrium partition function and base pair binding probabilities for RNA secondary structure},
  author={John S. McCaskill},
A novel application of dynamic programming to the folding problem for RNA enables one to calculate the full equilibrium partition function for secondary structure and the probabilities of various substructures. In particular, both the partition function and the probabilities of all base pairs are computed by a recursive scheme of polynomial order N3 in the sequence length N. The temperature dependence of the partition function gives information about melting behavior for the secondary structure… 
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  • S. Freier, R. Kierzek, D. Turner
  • Biology, Chemistry
    Proceedings of the National Academy of Sciences of the United States of America
  • 1986
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