The epigenetic effects of butyrate: potential therapeutic implications for clinical practice

@inproceedings{Canani2012TheEE,
  title={The epigenetic effects of butyrate: potential therapeutic implications for clinical practice},
  author={Roberto Berni Canani and Margherita di Costanzo and Ludovica Leone},
  booktitle={Clinical Epigenetics},
  year={2012}
}
Butyrate is a short chain fatty acid derived from the microbial fermentation of dietary fibers in the colon. In the last decade, multiple beneficial effects of butyrate at intestinal and extraintestinal level have been demonstrated. The mechanisms of action of butyrate are different and many of these involve an epigenetic regulation of gene expression through the inhibition of histone deacetylase. There is a growing interest in butyrate because its impact on epigenetic mechanisms will lead to… CONTINUE READING
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