The epigenetic basis for centromere identity.

  title={The epigenetic basis for centromere identity.},
  author={Tanya Panchenko and Ben E. Black},
  journal={Progress in molecular and subcellular biology},
The centromere serves as the control locus for chromosome segregation at mitosis and meiosis. In most eukaryotes, including mammals, the location of the centromere is epigenetically defined. The contribution of both genetic and epigenetic determinants to centromere function is the subject of current investigation in diverse eukaryotes. Here we highlight key… CONTINUE READING