The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.

@article{Perugorria2008TheEG,
  title={The epidermal growth factor receptor ligand amphiregulin participates in the development of mouse liver fibrosis.},
  author={Maria J Perugorria and Mar{\'i}a Ujue Latasa and Alexandra Nicou and Hugo Cartagena-Lirola and Josefa Castillo and Saioa Go{\~n}i and Umberto Vespasiani-Gentilucci and Maria Giovanna Zagami and Sophie Lotersztajn and Jes{\'u}s Prieto and Carmen Berasain and Mat{\'i}as A. Avila},
  journal={Hepatology},
  year={2008},
  volume={48 4},
  pages={1251-61}
}
UNLABELLED The hepatic wound-healing response to chronic noxious stimuli may lead to liver fibrosis, a condition characterized by excessive deposition of extracellular matrix. Fibrogenic cells, including hepatic stellate cells and myofibroblasts, are activated in response to a variety of cytokines, growth factors, and inflammatory mediators. The involvement… CONTINUE READING