The epidemiology of pain in Parkinson’s disease

  title={The epidemiology of pain in Parkinson’s disease},
  author={Giovanni Defazio and Angelo Gigante and Paola Mancino and Michele Tinazzi},
  journal={Journal of Neural Transmission},
Pain occurring in Parkinson’s disease (PD) may affect a large proportion of patients. Based on the results of the methodologically more robust case–control studies that detected a significantly greater frequency of pain in PD patients than in control subjects, pain should now be considered as a non-motor symptom of PD. The heterogeneous quality of pain, the variable relationship of pain with parkinsonian motor signs, and the mixed response of pain to dopaminergic drugs suggest complex… CONTINUE READING

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Pain as a nonmotor symptom of Parkinson’s disease

  • G Defazio, A Berardelli, G Fabbrini
  • Arch Neurol
  • 2008
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