The epidemiology of childhood pneumococcal disease in the United States in the era of conjugate vaccine use.

@article{Toltzis2005TheEO,
  title={The epidemiology of childhood pneumococcal disease in the United States in the era of conjugate vaccine use.},
  author={Philip Toltzis and Michael R. Jacobs},
  journal={Infectious disease clinics of North America},
  year={2005},
  volume={19 3},
  pages={629-45}
}
In 2000, a heptavalent pneumococcal conjugate vaccine was licensed and included in the schedule of routine childhood immunizations in the United States. The vaccine contains the serotypes most commonly associated with invasive and noninvasive pneumococcal infection in children and the serotypes most commonly expressing antibiotic resistance. Since the introduction of the vaccine, the incidence of invasive pneumococcal disease has declined dramatically in the United States, particularly among… CONTINUE READING

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