The ephrins and Eph receptors in neural development.

@article{Flanagan1998TheEA,
  title={The ephrins and Eph receptors in neural development.},
  author={J. Flanagan and Pierre Vanderhaeghen},
  journal={Annual review of neuroscience},
  year={1998},
  volume={21},
  pages={
          309-45
        }
}
The Eph receptors are the largest known family of receptor tyrosine kinases. Initially all of them were identified as orphan receptors without known ligands, and their specific functions were not well understood. During the past few years, a corresponding family of ligands has been identified, called the ephrins, and specific functions have now been identified in neural development. The ephrins and Eph receptors are implicated as positional labels that may guide the development of neural… 

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