• Corpus ID: 17567015

The environmental side effects of medication How are human and veterinary medicines in soils and water bodies affecting human and environmental health ?

@inproceedings{Boxall2004TheES,
  title={The environmental side effects of medication How are human and veterinary medicines in soils and water bodies affecting human and environmental health ?},
  author={Alistair B.A. Boxall},
  year={2004}
}
Medicines have an important role in the treatment and prevention of disease in both humans and animals. But it is because of the very nature of medicines that they may also have unintended effects on animals and microorganisms in the environment. Although the side effects on human and animal health are usually investigated in thorough safety and toxicology studies, the potential environmental impacts of the manufacture and use of medicines are less well understood and have only recently become… 

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References

SHOWING 1-10 OF 37 REFERENCES

Veterinary medicines in the environment.

The impact of veterinary medicines on the environment will depend on a number of factors including physicochemical properties, amount used and method of administration, treatment type and dose,

Pharmaceuticals and personal care products in the environment: Regulatory drivers and research needs

An overview of the regulatory assessment of pharmaceuticals and personal care products (PPCPs) is provided and will expand on many of the topics for research in the future, and the role that QSAR scientists can play in this research will be highlighted.

Pharmaceuticals and personal care products in the environment: agents of subtle change?

This review attempts to synthesize the literature on environmental origin, distribution/occurrence, and effects and to catalyze a more focused discussion in the environmental science community.

Occurrence of antibiotics in the aquatic environment.

Pharmaceuticals in the Canadian Environment

One of the first reports of the release of pharmaceutically active compounds (PhACs) into the environment was a study conducted in Canada on the concentrations of selected drugs in the effluent from

Plasma Concentrations of Human Pharmaceuticals as Predictors of Pharmacological Responses in Fish

The model can provide a framework and prioritisation tool for considering pharmaceutical responses in fish and indicates that pharmaceuticals may partition from water into fish plasma.

Sorption of veterinary pharmaceuticals in soils: a review.

  • J. Tolls
  • Chemistry, Medicine
    Environmental science & technology
  • 2001
The compilation of sorption coefficients to soil solids (Kd,solid) demonstrates that these chemicals display a wide range of mobility, and suggests that mechanisms other than hydrophobic partitioning play a significant role in sorption of VPs.