The enigma of coproporphyrinogen oxidase: how does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups?

  • Timothy D Lash
  • Published 2005 in Bioorganic & medicinal chemistry letters

Abstract

A new mechanism is proposed to explain how coproporphyrinogen oxidase performs two oxidative decarboxylations on a porphyrinogen substrate without the aid of cofactors or metal ions in the presence of molecular oxygen. 

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Cite this paper

@article{Lash2005TheEO, title={The enigma of coproporphyrinogen oxidase: how does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups?}, author={Timothy D Lash}, journal={Bioorganic & medicinal chemistry letters}, year={2005}, volume={15 20}, pages={4506-9} }