The endoplasmic reticulum stress response: A link with tuberculosis?

@article{Cui2016TheER,
  title={The endoplasmic reticulum stress response: A link with tuberculosis?},
  author={Yongyong Cui and Deming Zhao and Paul Barrow and Xiangmei Zhou},
  journal={Tuberculosis},
  year={2016},
  volume={97},
  pages={52-6}
}
Tuberculosis (TB) remains a major cause of mortality and morbidity in the worldwide. The endoplasmic-reticulum stress (ERS) response constitutes a cellular process that is triggered by mycobacterial infection that disturbs the folding of proteins in the endoplasmic reticulum (ER). The unfolded protein response (UPR) is induced to suspend the synthesis of early proteins and reduce the accumulation of unfolded- or misfolded proteins in the ER restoring normal physiological cell function… CONTINUE READING

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