The endocrinology of menstruation--a role for the immune system.

  title={The endocrinology of menstruation--a role for the immune system.},
  author={Hilary Octavia Dawn Critchley and Rodney W. Kelly and Robert M. Brenner and DavidT. Baird},
  journal={Clinical endocrinology},
  volume={55 6},
The human endometrium displays characteristic features, both structural and functional, across the menstrual cycle. It is the sex steroid hormones, oestrogen and progesterone, that drive the endometrium through the different phases of the cycle. Oestrogen and progesterone act sequentially to regulate cellular concentrations of their respective receptors, this interaction initiates gene transcription. Thereafter a cascade of local events prepares the endometrium for implantation, but in the… CONTINUE READING


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