The endocrine function of the heart.

  title={The endocrine function of the heart.},
  author={Monica Forero McGrath and Mercedes L Kuroski de Bold and Adolfo J. de Bold},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={16 10},
Atrial cardiocytes in the heart of mammals produce in a regulated manner the polypeptide hormones atrial natriuretic factor (ANF, ANP) and brain natriuretic peptide (BNP). The biological actions of ANF and BNP are similar; they include the modulation of systems that tend to increase extracellular fluid volume and blood pressure, such as the renin-angiotensin system and the sympathetic nervous system. Additionally, both hormones have potent growth-regulating properties. ANF and BNP signal by… CONTINUE READING


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