The endless quest for sex determination genes

@article{Fleming2005TheEQ,
  title={The endless quest for sex determination genes},
  author={Alice Fleming and Eric Vilain},
  journal={Clinical Genetics},
  year={2005},
  volume={67}
}
Disorders in human sex determination cause defects in gonadal function and can result in a spectrum of abnormalities in the internal and external genitalia, ranging from relatively mild sexual ambiguities to complete sex reversal. Several genes involved in sex determination have been validated in humans, and activities of their gene products are being elucidated, particularly in mouse models. However, how these genes interact in an overall process remains far from clear, and it is probable that… 
[Genetic background of sex determination and gonadal development disorders].
  • R. Piprek
  • Biology, Medicine
    Endokrynologia Polska
  • 2008
TLDR
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