The end of the (DNA) line

@article{Blackburn2000TheEO,
  title={The end of the (DNA) line},
  author={Elizabeth H Blackburn},
  journal={Nature Structural Biology},
  year={2000},
  volume={7},
  pages={847-850}
}
Telomerases contain an essential RNA subunit (TER), as well as an essential protein reverse transcriptase subunit (TERT). The RNA subunit includes a short template region that is copied into telomeric DNA, but otherwise it is large and divergent. However, phylogenetic studies have revealed a conserved core secondary structure for TER. Much of the divergence… CONTINUE READING