The enantioselective hydrolysis of racemic naproxen methyl ester in supercritical CO2 using Candida rugosa lipase

@inproceedings{Salgn2007TheEH,
  title={The enantioselective hydrolysis of racemic naproxen methyl ester in supercritical CO2 using Candida rugosa lipase},
  author={Uǧur Salgın and Sema Salgın and Serpil Takaç},
  year={2007}
}
Abstract The enantioselective hydrolysis of racemic naproxen methyl ester by Candida rugosa lipase (CRL) was studied in aqueous buffer solution/isooctane reaction system in the presence of supercritical CO 2 . The effects pressure (75–160 bar), temperature (32–42 °C) and reaction time (0.5–12 h) on the enantiomeric excesses of the product (ee p ) and the substrate (ee s ), enantiomeric ratio ( E ), conversion ( x ) and enzyme activity were investigated in a batch reactor system. The highest… CONTINUE READING