The enamelin genes in lizard, crocodile, and frog and the pseudogene in the chicken provide new insights on enamelin evolution in tetrapods.

@article{AlHashimi2010TheEG,
  title={The enamelin genes in lizard, crocodile, and frog and the pseudogene in the chicken provide new insights on enamelin evolution in tetrapods.},
  author={Nawfal Al-Hashimi and Anne-Gaelle Lafont and S Delgado and Kazuhiko Kawasaki and Jean-yves Sire},
  journal={Molecular biology and evolution},
  year={2010},
  volume={27 9},
  pages={2078-94}
}
Enamelin (ENAM) has been shown to be a crucial protein for enamel formation and mineralization. Previous molecular analyses have indicated a probable origin early in vertebrate evolution, which is supported by the presence of enamel/enameloid tissues in early vertebrates. In contrast to these hypotheses, ENAM was only characterized in mammals. Our aims were to 1) look for ENAM in representatives of nonmammalian tetrapods, 2) search for a pseudogene in the chicken genome, and 3) see whether the… CONTINUE READING