The emerging roles of forkhead box (Fox) proteins in cancer

@article{Myatt2007TheER,
  title={The emerging roles of forkhead box (Fox) proteins in cancer},
  author={Stephen S. Myatt and Eric Wing-Fai Lam},
  journal={Nature Reviews Cancer},
  year={2007},
  volume={7},
  pages={847-859}
}
Forkhead box (Fox) proteins are a superfamily of evolutionarily conserved transcriptional regulators, which control a wide spectrum of biological processes. As a consequence, a loss or gain of Fox function can alter cell fate and promote tumorigenesis as well as cancer progression. Here we discuss the evidence that the deregulation of Fox family transcription factors has a crucial role in the development and progression of cancer, and evaluate the emerging role of Fox proteins as direct and… 
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