The emerging roles of deubiquitylating enzymes (DUBs) in the TGFβ and BMP pathways


The members of the transforming growth factor beta (TGFβ) family of cytokines, including bone morphogenetic proteins (BMP), play fundamental roles in development and tissue homeostasis. Hence, aberrant TGFβ/BMP signalling is associated with several human diseases such as fibrosis, bone and immune disorders, cancer progression and metastasis. Consequently… (More)
DOI: 10.1016/j.cellsig.2014.06.012


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