The emerging role of the TIM molecules in transplantation.

Abstract

Since their discovery in 2001, the T-cell immunoglobulin mucin (TIM) family members have been shown to play important roles in the regulation of immune responses. The TIM family comprises of eight genes in the mouse, three of which are conserved in humans (TIM-1, TIM-3 and TIM-4). Initially, TIM-1 and TIM-3 were thought to be expressed solely on T cells… (More)
DOI: 10.1111/j.1600-6143.2011.03727.x

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