The emerging role of targeting cancer metabolism for cancer therapy
@article{Farhadi2020TheER, title={The emerging role of targeting cancer metabolism for cancer therapy}, author={Pegah Farhadi and Reza Yarani and Sadat Dokaneheifard and Kamran Mansouri}, journal={Tumor Biology}, year={2020}, volume={42} }
Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics differently. Tumor cells’ dependency to aerobic glycolysis and other cancer-specific metabolism changes are known as the cancer hallmarks, distinct cancer cells from normal cells. Therefore, these tumor-specific characteristics receive the limelight…
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