The emerging role of targeting cancer metabolism for cancer therapy

  title={The emerging role of targeting cancer metabolism for cancer therapy},
  author={Pegah Farhadi and Reza Yarani and Sadat Dokaneheifard and Kamran Mansouri},
  journal={Tumor Biology},
Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics differently. Tumor cells’ dependency to aerobic glycolysis and other cancer-specific metabolism changes are known as the cancer hallmarks, distinct cancer cells from normal cells. Therefore, these tumor-specific characteristics receive the limelight… Expand

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