The emerging role of targeting cancer metabolism for cancer therapy
@article{Farhadi2020TheER, title={The emerging role of targeting cancer metabolism for cancer therapy}, author={Pegah Farhadi and Reza Yarani and Sadat Dokaneheifard and K. Mansouri}, journal={Tumor Biology}, year={2020}, volume={42} }
Glucose, as the main consuming nutrient of the body, faces different destinies in cancer cells. Glycolysis, oxidative phosphorylation, and pentose phosphate pathways produce different glucose-derived metabolites and thus affect cells’ bioenergetics differently. Tumor cells’ dependency to aerobic glycolysis and other cancer-specific metabolism changes are known as the cancer hallmarks, distinct cancer cells from normal cells. Therefore, these tumor-specific characteristics receive the limelight… CONTINUE READING
One Citation
Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases
- Medicine
- International journal of molecular sciences
- 2021
References
SHOWING 1-10 OF 228 REFERENCES
Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism
- Biology, Medicine
- Redox biology
- 2017
- 74
The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
- Chemistry, Medicine
- Biomolecules & therapeutics
- 2018
- 46
- PDF
Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?
- Biology, Medicine
- International journal of biological sciences
- 2015
- 75
- PDF
Inhibition of Glycolysis and Glutaminolysis: An Emerging Drug Discovery Approach to Combat Cancer
- Chemistry, Medicine
- Current topics in medicinal chemistry
- 2018
- 52
- PDF
Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- Medicine
- Clinical Cancer Research
- 2018
- 165
- PDF
Cancer cells change their glucose metabolism to overcome increased ROS: One step from cancer cell to cancer stem cell?
- Chemistry, Medicine
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 2019
- 20
Defining the molecular basis of tumor metabolism: a continuing challenge since Warburg's discovery.
- Biology, Medicine
- Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
- 2011
- 22
Fatty acid oxidation: An emerging facet of metabolic transformation in cancer.
- Biology, Medicine
- Cancer letters
- 2018
- 42