The emerging role of promiscuous 7TM receptors as chemosensors for food intake.

@article{Wellendorph2010TheER,
  title={The emerging role of promiscuous 7TM receptors as chemosensors for food intake.},
  author={Petrine Wellendorph and Lars Dan Johansen and Hans Br{\"a}uner-Osborne},
  journal={Vitamins and hormones},
  year={2010},
  volume={84},
  pages={151-84}
}
In recent years, several highly promiscuous seven transmembrane (7TM) receptors have been cloned and characterized of which many are activated broadly by amino acids, proteolytic degradation products, carbohydrates, or free fatty acids (FFAs) and are expressed in taste tissue, the gastrointestinal (GI) tract, endocrine glands, adipose tissue, and/or kidney. This has led to the hypothesis that these receptors may act as sensors of food intake modulating, for example, release of incretin hormones… CONTINUE READING

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