The emerging role of miR-375 in cancer.

  title={The emerging role of miR-375 in cancer.},
  author={Jun-Wei Yan and Ju-sheng Lin and Xing-Xing He},
  journal={International journal of cancer},
  volume={135 5},
MicroRNAs (miRNAs) are evolutionarily conserved, small noncoding RNAs that are believed to play fundamental roles in various biological processes through regulation of gene expression at the level of posttranscription. MiR-375 was first identified as a pancreatic islet-specific miRNA regulating insulin secretion. However, further study revealed that miR-375 is a multifunctional miRNA participating in pancreatic islet development, glucose homeostasis, mucosal immunity, lung surfactant secretion… CONTINUE READING
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