The emerging role of class-3 semaphorins and their neuropilin receptors in oncology

@inproceedings{Nasarre2014TheER,
  title={The emerging role of class-3 semaphorins and their neuropilin receptors in oncology},
  author={Patrick Nasarre and Robert M Gemmill and Harry A. Drabkin},
  booktitle={OncoTargets and therapy},
  year={2014}
}
The semaphorins, discovered over 20 years ago, are a large family of secreted or transmembrane and glycophosphatidylinositol -anchored proteins initially identified as axon guidance molecules crucial for the development of the nervous system. It has now been established that they also play important roles in organ development and function, especially involving the immune, respiratory, and cardiovascular systems, and in pathological disorders, including cancer. During tumor progression… CONTINUE READING

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Semaphorin Signaling in Cancer-Associated Inflammation

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  • 2018
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