The emerging role of VHS domain-containing Tom1, Tom1L1 and Tom1L2 in membrane trafficking.

@article{Wang2010TheER,
  title={The emerging role of VHS domain-containing Tom1, Tom1L1 and Tom1L2 in membrane trafficking.},
  author={Tuanlao Wang and Ning Sheng Liu and Li-Fong Seet and Wanjin Hong},
  journal={Traffic},
  year={2010},
  volume={11 9},
  pages={1119-28}
}
The maintenance of cellular homeostasis and execution of regulatory mechanisms to dynamically govern various cellular processes require the correct delivery of proteins to their target subcellular compartments. It is estimated that over 30% of the proteins encoded by the human genome, projected to encode about 25 000 proteins and other macromolecules, are delivered to the secretory and endocytic pathways where movement of proteins between various compartments is primarily mediated by vesicles… CONTINUE READING

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