The emerging role of NG2 in pediatric diffuse intrinsic pontine glioma

@inproceedings{Yadavilli2015TheER,
  title={The emerging role of NG2 in pediatric diffuse intrinsic pontine glioma},
  author={Sridevi Yadavilli and Joseph Scafidi and Oren J. Becher and Amanda Muhs Saratsis and Rebecca L. Hiner and Madhuri Kambhampati and Santi Mariarita and Tobey J Macdonald and Kari-Elise T. Codispoti and Suresh N. Magge and Jyoti K Jaiswal and Roger J. Packer and Javad Nazarian},
  booktitle={Oncotarget},
  year={2015}
}
Diffuse intrinsic pontine gliomas (DIPGs) have a dismal prognosis and are poorly understood brain cancers. Receptor tyrosine kinases stabilized by neuron-glial antigen 2 (NG2) protein are known to induce gliomagenesis. Here, we investigated NG2 expression in a cohort of DIPG specimens (n= 50). We demonstrate NG2 expression in the majority of DIPG specimens… CONTINUE READING