The emerging human pathogen Photorhabdus asymbiotica is a facultative intracellular bacterium and induces apoptosis of macrophage-like cells.

@article{Costa2009TheEH,
  title={The emerging human pathogen Photorhabdus asymbiotica is a facultative intracellular bacterium and induces apoptosis of macrophage-like cells.},
  author={Sonia C. P. Costa and Pierre Alain Girard and Michel Breh{\'e}lin and Robert Zumbihl},
  journal={Infection and immunity},
  year={2009},
  volume={77 3},
  pages={1022-30}
}
Photorhabdus species are gram-negative entomopathogenic bacteria of the family Enterobacteriaceae. Among the different members of the genus, one species, Photorhabdus asymbiotica, is a pathogen of both insects and humans. The pathogenicity mechanisms of this bacterium are unknown. Here we show that P. asymbiotica is a facultative intracellular pathogen that is able to replicate inside human macrophage-like cells. Furthermore, P. asymbiotica was shown for the first time in an intracellular… CONTINUE READING
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