The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses.

@article{Serkova2011TheEF,
  title={The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses.},
  author={Natalie J. Serkova and Theodore J Standiford and Kathleen A. Stringer},
  journal={American journal of respiratory and critical care medicine},
  year={2011},
  volume={184 6},
  pages={647-55}
}
Metabolomics, a science of systems biology, is the global assessment of endogenous metabolites within a biologic system and represents a "snapshot" reading of gene function, enzyme activity, and the physiological landscape. Metabolite detection, either individual or grouped as a metabolomic profile, is usually performed in cells, tissues, or biofluids by either nuclear magnetic resonance spectroscopy or mass spectrometry followed by sophisticated multivariate data analysis. Because loss of… CONTINUE READING
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