The emergence of the two cell fates and their associated switching for a negative auto-regulating gene

@article{Jiang2019TheEO,
  title={The emergence of the two cell fates and their associated switching for a negative auto-regulating gene},
  author={Zhenlong Jiang and Li Tian and Xiaona Fang and Kun Zhang and Qiong Liu and Qingzhe Dong and Erkang Wang and Jin Wang},
  journal={BMC Biology},
  year={2019},
  volume={17}
}
BackgroundDecisions in the cell that lead to its ultimate fate are important for fundamental cellular functions such as proliferation, growth, differentiation, development, and death. These cell fate decisions can be influenced by both the gene regulatory network and also environmental factors and can be modeled using simple gene feedback circuits. Negative auto-regulation is a common feedback motif in the gene circuits. It can act to reduce gene expression noise or induce oscillatory… 
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