The emergence of the glomerular parietal epithelial cell

  title={The emergence of the glomerular parietal epithelial cell},
  author={Stuart J. Shankland and Bart Smeets and Jeffrey W. Pippin and Marcus M{\"o}ller},
  journal={Nature Reviews Nephrology},
Glomerular diseases are the leading causes of chronic and end-stage kidney disease. In the 1980s and 1990s, attention was focused on the biology and role of glomerular endothelial and mesangial cells. For the past two decades, seminal discoveries have been made in podocyte biology in health and disease. More recently, the glomerular parietal epithelial cell (PEC)—the fourth resident glomerular cell type—has been under active study, leading to a better understanding and definition of how these… CONTINUE READING
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