The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.

@article{Tan2017TheEO,
  title={The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.},
  author={Su-Fern Tan and Jennifer M Pearson and David J Feith and Thomas P. Loughran},
  journal={Expert opinion on therapeutic targets},
  year={2017},
  volume={21 6},
  pages={583-590}
}
INTRODUCTION Acute myeloid leukemia (AML) is the most common adult leukemia. Only a fraction of AML patients will survive with existing chemotherapy regimens. Hence, there is an urgent and unmet need to identify novel targets and develop better therapeutics in AML. In the past decade, the field of sphingolipid metabolism has emerged into the forefront of cancer biology due to its importance in cancer cell proliferation and survival. In particular, acid ceramidase (AC) has emerged as a promising… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
2 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…