The emergence of Streptococcus pneumoniae resistant to macrolide antimicrobial agents: a 6-year population-based assessment.

@article{Gay2000TheEO,
  title={The emergence of Streptococcus pneumoniae resistant to macrolide antimicrobial agents: a 6-year population-based assessment.},
  author={Kathryn Gay and Wendy S Baughman and Yifat Miller and Delois Jackson and Cynthia G. Whitney and Anne Schuchat and Monica M. Farley and Fred C. Tenover and David S. Stephens},
  journal={The Journal of infectious diseases},
  year={2000},
  volume={182 5},
  pages={1417-24}
}
From 1994 through 1999, the available isolates (4148 isolates) from active population-based surveillance of invasive pneumococcal disease in metropolitan Atlanta were serotyped and were tested for antimicrobial susceptibility. Macrolide-resistant isolates were studied for the presence of ermAM (a ribosomal methylase gene), mefE (a macrolide efflux gene), and tetM (the class M tetracycline resistance gene). Macrolide resistance increased from 16% of all invasive isolates in 1994 to 32% in 1999… CONTINUE READING

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References

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Showing 1-10 of 44 references

Clinical significance of resistant organisms in otitis media.

The Pediatric infectious disease journal • 2000

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