The elevated interferon gamma production is an important immunological marker in HAM/TSP pathogenesis.


Human T-lymphotropic virus type 1 (HTLV-1) is the agent of the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), which may occur in >5% of patients during their lifetime. HTLV-1-infection causes disturbances in the immune system, and the viral load may also play an important role in the pathogenesis of HAM/TSP. Some cytokines are involved… (More)
DOI: 10.1111/j.1365-3083.2009.02291.x

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