The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice.

@article{Khan2005TheE1,
  title={The elevated 10-year risk of cervical precancer and cancer in women with human papillomavirus (HPV) type 16 or 18 and the possible utility of type-specific HPV testing in clinical practice.},
  author={Michelle J Khan and Philip E. Castle and Attila T Lorincz and Sholom Wacholder and Mark E. Sherman and David R Scott and Brenda B. Rush and Andrew Glass and Mark Schiffman},
  journal={Journal of the National Cancer Institute},
  year={2005},
  volume={97 14},
  pages={1072-9}
}
BACKGROUND Human papillomavirus (HPV) types 16 and 18 cause 60%-70% of cervical cancer worldwide, and other HPV types cause virtually all remaining cases. Pooled HPV testing for 13 oncogenic types, including HPV16 and 18, is currently used in clinical practice for triage of equivocal cytology and, in conjunction with Pap tests, is an option for general screening among women 30 years of age and older. It is not clear to what extent individual identification of HPV16 or HPV18 as an adjunct to… CONTINUE READING
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