The electrophysiological characteristics of hypertrophied ventricular myocytes from the spontaneously hypertensive rat.

@article{Brooksby1993TheEC,
  title={The electrophysiological characteristics of hypertrophied ventricular myocytes from the spontaneously hypertensive rat.},
  author={P Brooksby and Allan J. Levi and J Vann Jones},
  journal={Journal of hypertension},
  year={1993},
  volume={11 6},
  pages={611-22}
}
OBJECTIVE Previous studies on multicellular preparations have shown that hypertrophied cardiac muscle from the spontaneously hypertensive rat (SHR) has a prolonged action potential. The first aim of the present study was to determine whether the action potential of isolated left ventricular myocytes was similarly prolonged and to study the underlying membrane currents that might be responsible. The second aim was to evaluate the L-type calcium current amplitude of SHR myocytes, as we have… CONTINUE READING