The electron transfer reactions of NADPH: cytochrome P450 reductase with nonphysiological oxidants.

@article{nas1994TheET,
  title={The electron transfer reactions of NADPH: cytochrome P450 reductase with nonphysiological oxidants.},
  author={Narimantas K. {\vC}ėnas and Žilvinas Anusevi{\vc}ius and Daiva Bironaite and G I Bachmanova and Alexander I. Archakov and Karin M Ollinger},
  journal={Archives of biochemistry and biophysics},
  year={1994},
  volume={315 2},
  pages={400-6}
}
The steady-state kinetics of oxidation of rat liver NADPH: cytochrome P450 reductase (EC 1.6.2.4) by quinones, aromatic nitrocompounds, ferricyanide, Fe(EDTA)-, and cytochrome c has been studied. The logarithms of bimolecular rate constants of reduction (kcat/Km) of quinones and nitrocompounds increase with the increase in their single-electronreduction potential (E1(7)), reaching a maximum value at E1(7) > -0.15 V. The reactivities of nitroaromatics are about by an order of magnitude lower… CONTINUE READING
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