The efficiency of humectants as skin moisturizers in the presence of oil

@article{Sagiv2001TheEO,
  title={The efficiency of humectants as skin moisturizers in the presence of oil},
  author={Assaf E Sagiv and Shabtay Dikstein and Arieh Ingber},
  journal={Skin Research and Technology},
  year={2001},
  volume={7}
}
Background/aims: The research on the treatment of “dry skin syndrome” is hampered by the lack of a suitable animal model. Formerly, we developed a validated guinea pig in vivo model in which the dry skin syndrome persists at least for 1 week. We can, therefore, compare the pharmacological effectiveness of known and potential moisturizers for the treatment of dry skin syndrome. Our aim is to study whether the moisturizing efficiency of humectants depends on the solvents in which they are… 
The connection between in vitro water uptake and in vivo skin moisturization
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TLDR
Humectancy or hygroscopy is the water absorption tendency of a substance from the surroundings and its effect in vivo for the development of drugs and formulations for the treatment of dry skin syndrome or diseases accompanied by dry skin.
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References

SHOWING 1-4 OF 4 REFERENCES
A novel in vivo model in guinea pigs for dry skin syndrome
  • A. E. Sagiv, A. Ingber, S. Dikstein
  • Medicine
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging
  • 2000
TLDR
The lack of a suitable, validated animal model for the comparison of the pharmacological effectiveness of known and potential moisturizers in the treatment of “dry skin syndrome” led to the development of an in vivo model.
Comparison of different instruments for measuring stratum corneum moisture content
Stratum corneum moisturization was measured by two instruments simultaneously on the same subjects at different body sites. One instrument is based on the 1 GHz focused mirowave dielectric
Comparison of different instruments for measuring SC moisture content
  • Int J Cosmet Sci Address
  • 1986