The efficiency and timing of initiation of replication of multiple replicons of Saccharomyces cerevisiae chromosome VI.

@article{Yamashita1997TheEA,
  title={The efficiency and timing of initiation of replication of multiple replicons of Saccharomyces cerevisiae chromosome VI.},
  author={Masakane Yamashita and Yuji Hori and T. Shinomiya and Chikashi Obuse and Toshiki Tsurimoto and Hirofumi Yoshikawa and Katsuhiko Shirahige},
  journal={Genes to cells : devoted to molecular & cellular mechanisms},
  year={1997},
  volume={2 11},
  pages={655-65}
}
BACKGROUND A complete set of nine ARSs was identified (the tenth ARS in this paper), mapped on chromosome VI of Saccharomyces cerevisiae, and characterized for functional elements. RESULTS The level of activity of all ARSs as chromosomal replication origins was determined by neutral/neutral 2D gel-electrophoresis. These origins were classified into three groups: (i) three high frequency origins used once nearly every cell cycle, (ii) four intermediate frequency origins used once in two to… CONTINUE READING

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