The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates.

@article{Siu1998TheEO,
  title={The efficacy of vitamin E and melatonin as antioxidants against lipid peroxidation in rat retinal homogenates.},
  author={Andrew W. Siu and Russell J Reiter and Chi Ho To},
  journal={Journal of pineal research},
  year={1998},
  volume={24 4},
  pages={239-44}
}
Free radical-induced oxidation can cause severe cell damage in biological systems. Melatonin, a pineal secretory product, is a recently identified antioxidant that protects cells from the damaging effects of free radicals. We compared the effect of melatonin and vitamin E, another antioxidant, against lipid peroxidation (LPO) in rat retinal homogenates. The aim was to characterize the antioxidative efficacy of melatonin in retina, a tissue highly susceptible to oxidative damage. The LPO product… CONTINUE READING

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