The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta‐analysis of randomized clinical trials

  title={The efficacy of sour tea (Hibiscus sabdariffa L.) on selected cardiovascular disease risk factors: A systematic review and meta‐analysis of randomized clinical trials},
  author={Saeid Najafpour Boushehri and Razieh Karimbeiki and Sara Ghasempour and Samira-Sadat Ghalishourani and Makan Pourmasoumi and Amir Hadi and Muniirah Mbabazi and Ziyaaddin Keshavarzpour Pour and Mostafa Assarroudi and Marzieh Mahmoodi and Abdolrasool Khosravi and Fariborz Mansour-Ghanaei and Farahnaz Joukar},
  journal={Phytotherapy Research},
  pages={329 - 339}
This study sought to summarize clinical evidence of sour tea (Hibiscus sabdariffa L.) administration on cardiovascular disease risk factors. PubMed, Scopus, Institute for Scientific Information Web of Science, and Google Scholar were systematically searched from inception to June 2019 to identify randomized clinical trials, which assessed the effect of sour tea consumption on lipid profiles, fasting plasma glucose, and blood pressure in adult populations. Mean and standard deviation for each… 

A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers

Regular consumption of hibiscus could confer reduced cardiovascular disease risk, and more studies are warranted to establish an effective dose response and treatment duration.

Hibiscus Tea and Health: A Scoping Review of Scientific Evidence

Strongest evidence exists in relation to cardiovascular disease, suggesting that drinking 2-3 cups daily of hibiscus tea may improve blood pressure and potentially serve as a preventative or adjunctive therapy against such conditions.

Effect of sour tea supplementation on liver enzymes, lipid profile, blood pressure, and antioxidant status in patients with non‐alcoholic fatty liver disease: A double‐blind randomized controlled clinical trial

Sour tea supplementation may be effective in improving serum TG, liver enzymes, and blood pressure in patients diagnosed with NAFLD and the exact mechanism of action of these effects is needed to address.

Physiological Effects and Human Health Benefits of Hibiscus sabdariffa: A Review of Clinical Trials

The most-reported HS health benefits are its antihypertensive, antidyslipidemic, hypoglycemic, body fat mass reduction, nephroprotective, antianemic, antioxidant, anti-inflammatory, and anti-xerostomic activities; these effects are associated with the phytochemicals found in HS.

Methodologies in the Analysis of Phenolic Compounds in Roselle (Hibiscus sabdariffa L.): Composition, Biological Activity, and Beneficial Effects on Human Health

The applications of the analytical methods highlighted indicated that phenolic acids, flavonoids, and their derivatives have been identified and quantified in roselle with a range of biological activities and beneficial effects on human health.

Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.

Organic Acids from Roselle (Hibiscus sabdariffa L.)—A Brief Review of Its Pharmacological Effects

This review compiles information from published research on demonstrated pharmacological properties of organic acids found in Hibiscus sabdariffa L. to encourage and aid researchers to expand their studies on the pharmacologic and therapeutic effects of Hs to include assessments of the organic acid components.

Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease (NAFLD) evaluated by real‐time two‐dimensional shear wave elastography: A randomized clinical trial

Propolis seems to have protective effects on hepatic steatosis and fibrosis and to reduce the serum levels of hs‐CRP in patients with NAFLD.



Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials

A meta-analysis of RCTs showed a significant effect of H. sabdariffa supplementation in lowering both SBP and DBP values, which were inversely associated with baseline BP values, and were robust in sensitivity analyses.

Effects of Hibiscus sabdariffa L. on serum lipids: a systematic review and meta-analysis.

Effects of aqueous extracts of dried calyx of sour tea (Hibiscus sabdariffa L.) on polygenic dyslipidemia: A randomized clinical trial

Sour tea intake with recommended dietary patterns and physical activity can be useful in regulation of lipid profile in patients with polygenic dyslipidemia, and these effect might be attributed to its anthocyanins and inflation factors.

Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes.

The results of the present study showed that ST has a significant effect on blood lipid profile in patients with diabetes.

Does ginger supplementation lower blood pressure? A systematic review and meta‐analysis of clinical trials

It is revealed that ginger supplementation has favorable effects on BP, and further studies are warranted before definitive conclusions may be reached.

The impact of pycnogenol supplementation on plasma lipids in humans: A systematic review and meta‐analysis of clinical trials

The results indicate that pycnogenol supplementation improves levels of HDL‐C; however, the changes in TC, TAG, and LDL‐C were not clinically relevant.

Evaluation of the effects of roselle (Hibiscus sabdariffa L.) on oxidative stress and serum levels of lipids, insulin and hs-CRP in adult patients with metabolic syndrome: a double-blind placebo-controlled clinical trial

Daily consumption of 500 mg of H. sabdariffa L. calyx powder can decrease SBP and serum TG in MetS patients, and this plant is a plant with antihyperlipidemic and antihypertensive effects.

Effect of Hibiscus sabdariffa Calices on Dyslipidemia in Obese Adolescents: A Triple-masked Randomized Controlled Trial

It is concluded that Hibiscus sabdariffa calyces powder may have significant positive effects on lipid profile of adolescents which maybe attributed to its polyphenolic and antioxidant content.

Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension. A randomized, double-blind, lisinopril-controlled clinical trial.

In conclusion, the HsHMP exerted important antihypertensive effectiveness with a wide margin of tolerability and safety, while it also significantly reduced plasma ACE activity and demonstrated a tendency to reduce serum sodium concentrations without modifying potassium levels.

An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial

At a dose of 1 gm/day, hibiscus sabdariffa leaf extract did not appear to have a blood lipid lowering effect and it is likely that the observed effects were as a result of the patients following the standard dietary and physical activity advice.